Based on barker theory, babies with small birthweight have such as an adaptation to survive with their maternal malnourished. Then, this condition tend to be permanent as their next longlifetime. Their metabolism isn't like the other babies. Nevertheless, they also have high risk to experience degenerative diseases such as coronary heart disease, type 2 Diabetes melitus, Obesity, Aging, etc. I'm now very interesting with this topic. Wanna hear more? Then here you're...well, are you people with underweight birth? Or, have a baby with small birthweight? Watch out!
Baby borns so small (under 3 kg) can caused by several condition. Prematurity (baby borns before 34 weeks of pregnancy), failure maternal growth or IUGR (may caused by plasenta disfunction or maternal malnourished) have a big impact for Small Gestational Age (SGA) and may lead to the generative disease.
Let us go to obesity.
Baby borns small usually has immaturity organs and physiology. In the maternal condition they adapt with their malnourished mother to be survival. As the compensation, they decrease the amount of insulin produced by sel beta pancreas. It also decreases the glicogen stored in muscle and protect the central nervous system. It may explain why baby borns small has a weak tonus.
Supposed this baby then grow. The food is very easy to take and eat, their blood glucose will rises and insulin produced so low. it may lead to insulin resistance and may develop type 2 Diabetes Mellitus.
